Just as Richard has personally seen to the end of Buckingham, Anne confesses that her tuberculosis has returned. Anne begs Richard to disinherit their kind-hearted son Edward in order to protect him. Facing the cruel fate of loved ones drifting away, Richard desperate enough for the departed Buckingham to try replacing him with Catesby. But Catesby says he cannot, for "the heat of the body cannot warm the soul." In the midst of this, the battle with Richmond approaches.